The Relationship of Serum S100B Levels with Infarction Size and Clinical Outcome in Acute Ischemic Stroke Patients İskemik İnmeli Hastalarda Serum S100B Protein Düzeylerinin Lezyon Büyüklüğü ve Klinik Prognoz ile İlişkisi
نویسندگان
چکیده
Özlem SELÇUK1, Vildan YAYLA2, Murat ÇABALAR2, Vildan GÜZEL3, Samiye UYSAL2, Asuman GEDİKBAŞI4 1Bulanık State Hospital, Neurology Clinics, Muş, Turkey 2Bakırköy Dr. Sadi Konuk Education and Research Hospital, Neurology Clinics, İstanbul, Turkey 3Van Region Training and Research Hospital, Neurology Clinics, Van, Turkey 4Bakırköy Dr. Sadi Konuk Education and Research Hospital, Biochemistry Clinics, İstanbul, Turkey
منابع مشابه
The Relationship of Serum S100B Levels with Infarction Size and Clinical Outcome in Acute Ischemic Stroke Patients.
INTRODUCTION S100B protein, which helps nerve development and differentiation, is produced by astrocytes and can be detected in peripheral circulation after brain damage. In this study, we aimed to investigate the relationship between the serum S100B protein level and the infarction volume and clinical outcome and also the early prognostic role of serum S100B protein in patients with ischemic s...
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متن کاملCriteria for a clinically informative serum biomarker in acute ischaemic stroke: a review of S100B.
BACKGROUND AND PURPOSE Serum S100B has been widely studied as a biomarker in acute ischaemic stroke. The main objective of this review was to appraise the published literature on S100B and determine its clinical applicability. METHODS Medline was searched to identify studies on S100B (or S-100B) in acute ischaemic stroke. The authors have proposed the criteria for a clinically informative ser...
متن کاملElevated serum S100B levels indicate a higher risk of hemorrhagic transformation after thrombolytic therapy in acute stroke.
BACKGROUND AND PURPOSE Intracerebral hemorrhage constitutes an often fatal sequela of thrombolytic therapy in patients with ischemic stroke. Early blood-brain barrier disruption may play an important role, and the astroglial protein S100B is known to indicate blood-brain barrier dysfunction. We investigated whether elevated pretreatment serum S100B levels predict hemorrhagic transformation (HT)...
متن کاملGlial and axonal body fluid biomarkers are related to infarct volume, severity, and outcome.
Body fluid biomarkers of central nervous system damage may help improve the prognostic and diagnostic accuracy in ischemic stroke. We studied 53 patients. Stroke severity and outcome was rated using the National Institutes of Health Stroke Scale and modified Rankin scale. Ferritin, S100B, and NfH were measured in cerebrospinal fluid (CSF) and serum. Infarct volume was calculated from T2W images...
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